This article discusses the contribution of innovation centres in nearby neighbourhoods based on primary data. This paper involves the study of the case of Ruta N in Medellín to expose the relationship between a consolidated neighbourhood and new innovation facilities. Ruta N was founded after the implementation of a city-level policy for innovation intended to secure the economic growth of a former deprived area of the city. This innovation attracted local and international creative entrepreneurs to Medellín’s downtown but with inconsistent results. The analysis revealed that Ruta N rarely interacts with the nearby neighbourhood, thus restricting its potential to contribute to the community. Instead, it is perceived that Ruta N takes advantage of the neighbourhood to meet the needs of Ruta N users, not the other way around. As a result, community members argue that Ruta N could promote potential conflicts in the area.