The Anthropocene names the epoch wherein humans have become the main geological agent on the planet’s surface. But which humans, and since when? Dating the onset of the Anthropocene is a political and ontological as much as a scientific act. This essay argues the Anthropocene is inexorably racial because it flows out of a capitalist system which requires racializing populations and environments from early modernity to the present and into the future. The essay contends that racial capitalism should be a central category in explaining the onset of the Anthropocene. The focus will be on investigating whether it makes sense to take the European discovery of the Americas and the genocide against its original inhabitants as threshold of a new geological epoch. Following the radicalization of Marx in the philosophy of Deleuze and Guattari, it will be suggested that though colonization and slavery were essential for modern globalization to emerge, capital embarked on its self-perpetuating destructive trajectory through industrialization. Structural racism was transmuted and continues to characterize the global ecological crisis.